Article
Variants Fok1 and Bsm1 on VDR are associated with the melanoma risk: evidence from the published epidemiological studies.
BMC genetics - 11 Feb 2015
Hou Wei, Wan Xuefeng, Fan Junwei
Abstract excerpt
BACKGROUND: The vitamin D receptor (VDR) mediates the major cellular activities of vitamin D and regulates various signaling pathways implicated in cancer development and progression. VDR variants have been found associated with the risk of developing melanoma; however, previous epidemiological studies are inconsistent. We have systematically reviewed the published epidemiological literature and conducted a...
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