Article
Semiquantitative 123I-Metaiodobenzylguanidine Scintigraphy to Distinguish Pheochromocytoma and Paraganglioma from Physiologic Adrenal Uptake and Its Correlation with Genotype-Dependent Expression of Catecholamine Transporters.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine - 1 Jun 2015
van Berkel Anouk, Rao Jyotsna U, Lenders Jacques W M, Pellegata Natalia S, Kusters Benno, Piscaer Ianthe, Hermus Ad R M M, Plantinga Theo S, Langenhuijsen Johan F, Vriens Dennis, Janssen Marcel J R, Gotthardt Martin, Timmers Henri J L M
Abstract excerpt
UNLABELLED: (123)I-metaiodobenzylguanidine ((123)I-MIBG) scintigraphy plays an important role in the diagnostic evaluation of patients with pheochromocytoma and paraganglioma (PPGL). (123)I-MIBG targets cell membrane and vesicular catecholamine transporters of chromaffin cells and facilitates localization of the primary tumor and metastatic lesions. Its specificity for the diagnosis of adrenomedullary chromaffin...
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