Article
Modulating crossover positioning by introducing large structural changes in chromosomes.
BMC genomics - 15 Feb 2015
Ederveen Antoine, Lai Yuching, van Driel Marc A, Gerats Tom, Peters Janny L
Abstract excerpt
BACKGROUND: Crossing over assures the correct segregation of the homologous chromosomes to both poles of the dividing meiocyte. This exchange of DNA creates new allelic combinations thus increasing the genetic variation present in offspring. Crossovers are not uniformly distributed along chromosomes; rather there are preferred locations where they may take place. The positioning of crossovers is known to be...
Topics
- Arabidopsis
- Chromosome Deletion
- Chromosome Inversion
- Chromosomes, Plant
- Crossing Over, Genetic
- Gamma Rays
- Gene Frequency
- Genotype
- Loss of Heterozygosity
- Meiosis
- Recombination, Genetic
