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Article

Age at the time of sulfonylurea initiation influences treatment outcomes in KCNJ11-related neonatal diabetes.

Diabetologia - 1 Jul 2015

Thurber Brian W, Carmody David, Tadie Elizabeth C, Pastore Ashley N, Dickens Jazzmyne T, Wroblewski Kristen E, Naylor Rochelle N, Philipson Louis H, Greeley Siri Atma W

Abstract excerpt

AIMS/HYPOTHESIS: Individuals with heterozygous activating mutations of the KCNJ11 gene encoding a subunit of the ATP-sensitive potassium channel (KATP) can usually be treated with oral sulfonylurea (SU) pills in lieu of insulin injections. The aim of this study was to test our hypothesis that younger age at the time of initiation of SU therapy is correlated with lower required doses of SU therapy, shorter...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Potassium Channels, Inwardly Rectifying

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Source

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Identifiers

PMID: 25877689
DOI: 10.1007/s00125-015-3593-9
PMCID: PMC4641523

Genes

KCNJ11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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Age at the time of sulfonylurea initiation influences treatment outcomes in KCNJ11-related neonatal diabetes.PMID 25877689Read ↗

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