Article
[Detection of common deafness-related genes among non-syndromic deafness patients from Shanxi province].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Apr 2015
Zhou Yongan, Yang Huifang, Hao Ziqi, Ma Yunxia, Zhang Quanbin, Li Jiao, Zhao Xiaoli, Wang Xiang, Li Xiangshao, Xia Li, Ma Siqi
Abstract excerpt
OBJECTIVE: To explore the common causative genes and mutation sites for hereditary non-syndromic deafness in Shanxi. METHODS: Peripheral blood samples were collected from regional schools for children with deafness. The samples were analyzed by matrix-assisted laser desorption ionization of flight mass spectrometry, and the results were verified by DNA sequencing. RESULTS: For all samples, the 20 mutational sites...
Topics
- Adolescent
- Asian People
- Base Sequence
- Child
- China
- Connexin 26
- Connexins
- DNA Mutational Analysis
- Deafness
- Female
- Humans
- Male
- Molecular Sequence Data
- Mutation