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Molecular Mechanisms of Mitochondrial Autophagy/Mitophagy in the Heart

9 Apr 2015

Abstract excerpt

Mitochondrial quality is a crucial determinant of cell viability, and mitochondrial autophagy plays a central role in this control mechanism. Based on studies in yeast, numerous investigations of this process have been conducted, and the framework of mammalian mitochondrial autophagy is progressively appearing. However, many enigmas about the molecular mechanisms involved remain unsolved. Furthermore, the...

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PMID: 25858070
DOI: 10.1161/circresaha.116.303790

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