Article
Cell type-specific responses to wingless, hedgehog and decapentaplegic are essential for patterning early eye-antenna disc in Drosophila.
PloS one - 1 Jan 2015
Won Jong-Hoon, Tsogtbaatar Orkhon, Tsogtbartarr Orkhon, Son Wonseok, Singh Amit, Choi Kwang-Wook, Cho Kyung-Ok
Abstract excerpt
The Drosophila eye-antenna imaginal disc (ead) is a flattened sac of two-layered epithelia, from which most head structures are derived. Secreted morphogens like Wingless (Wg), Hedgehog (Hh), and Decapentaplegic (Dpp) are important for early patterning of ead, but the underlying mechanisms are still largely unknown. To understand how these morphogens function in the ead of early larval stages, we used wg-LacZ and...
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