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Article

Deep sequencing of the Trypanosoma cruzi GP63 surface proteases reveals diversity and diversifying selection among chronic and congenital Chagas disease patients.

PLoS neglected tropical diseases - 1 Apr 2015

Llewellyn Martin S, Messenger Louisa A, Luquetti Alejandro O, Garcia Lineth, Torrico Faustino, Tavares Suelene B N, Cheaib Bachar, Derome Nicolas, Delepine Marc, Baulard Céline, Deleuze Jean-Francois, Sauer Sascha, Miles Michael A

Abstract excerpt

BACKGROUND: Chagas disease results from infection with the diploid protozoan parasite Trypanosoma cruzi. T. cruzi is highly genetically diverse, and multiclonal infections in individual hosts are common, but little studied. In this study, we explore T. cruzi infection multiclonality in the contex...

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Identifiers

PMID: 25849488
DOI: 10.1371/journal.pntd.0003458
PMCID: PMC4388557

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25849488-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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