Article
Susceptibility to male infertility: replication study in Japanese men looking for an association with four GWAS-derived loci identified in European men.
Journal of assisted reproduction and genetics - 1 Jun 2015
Chihara Makoto, Yoshihara Kosuke, Ishiguro Tatsuya, Yokota Yuki, Adachi Sosuke, Okada Hiroyuki, Kashima Katsunori, Sato Takaaki, Tanaka Atsushi, Tanaka Kenichi, Enomoto Takayuki
Abstract excerpt
PURPOSE: A previous genome-wide association study in European men identified four single nucleotide polymorphism (SNP) loci associated with male infertility. Our aim was to replicate, if possible, the association of these SNPs with Japanese male infertility. METHODS: We genotyped four SNPs (rs5911500, rs10246939, rs2059807, and rs11204546) in 517 Japanese patients with male infertility and 369 fertile controls...
Read the complete abstract on PubMed