Article
Seven challenges in modeling pathogen dynamics within-host and across scales.
Epidemics - 1 Mar 2015
Gog Julia R, Pellis Lorenzo, Wood James L N, McLean Angela R, Arinaminpathy Nimalan, Lloyd-Smith James O
Abstract excerpt
The population dynamics of infectious disease is a mature field in terms of theory and to some extent, application. However for microparasites, the theory and application of models of the dynamics within a single infected host is still an open field. Further, connecting across the scales--from cellular to host level, to population level--has potential to vastly improve our understanding of pathogen dynamics and...
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