Article
Iron starvation induces apoptosis in Rhizopus oryzae in vitro.
Virulence - 1 Jan 2015
Shirazi Fazal, Kontoyiannis Dimitrios P, Ibrahim Ashraf S
Abstract excerpt
Mortality associated with mucormycosis remains high despite current antifungals. Iron-starvation strategies have been shown to have promising activity against Mucorales. We hypothesized that iron starvation enhances apoptosis in Rhizopus oryzae. Apoptosis was characterized in R. oryzae transformed with RNAi plasmid targeting FTR1 expression (iron permease mutant) or empty plasmid grown in iron rich (0.125% FeCl3)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
