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Article

Hyperhomocysteinemia and MTHFR polymorphisms as antenatal risk factors of white matter abnormalities in two cohorts of late preterm and full term newborns.

Oxidative medicine and cellular longevity - 1 Jan 2015

Marseglia Lucia M, Nicotera Antonio, Salpietro Vincenzo, Giaimo Elisa, Cardile Giovanna, Bonsignore Maria, Alibrandi Angela, Caccamo Daniela, Manti Sara, D'Angelo Gabriella, Mamì Carmelo, Di Rosa Gabriella

Abstract excerpt

Higher total homocysteine (tHcy) levels, and C677T and A1298C methylenetetrahydrofolate (MTHFR) polymorphisms, have been reported in preterm or full term newborns with neonatal encephalopathy following perinatal hypoxic-ischemic insult. This study investigated the causal role of tHcy and MTHFR po...

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Identifiers

PMID: 25829992
DOI: 10.1155/2015/543134
PMCID: PMC4338403

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25829992-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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