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Article

Identification of putative vaccine candidates against Helicobacter pylori exploiting exoproteome and secretome: a reverse vaccinology based approach.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jun 2015

Naz Anam, Awan Faryal Mehwish, Obaid Ayesha, Muhammad Syed Aun, Paracha Rehan Zafar, Ahmad Jamil, Ali Amjad

Abstract excerpt

Helicobacter pylori (H. pylori) is an important pathogen associated with diverse gastric disorders ranging from peptic ulcer to malignancy. It has also been recognized by the World Health Organization (WHO) as class I carcinogen. Conventional treatment regimens for H. pylori seem to be ineffective, possibly due to antibiotic resistance mechanisms acquired by the pathogen. In this study we have successfully...

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PMID: 25818402
DOI: 10.1016/j.meegid.2015.03.027

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