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Article

Identification of the neutralizing epitopes of Merkel cell polyomavirus major capsid protein within the BC and EF surface loops.

PloS one - 1 Jan 2015

Fleury Maxime J J, Nicol Jérôme T J, Samimi Mahtab, Arnold Françoise, Cazal Raphael, Ballaire Raphaelle, Mercey Olivier, Gonneville Hélène, Combelas Nicolas, Vautherot Jean-Francois, Moreau Thierry, Lorette Gérard, Coursaget Pierre, Touzé Antoine

Abstract excerpt

Merkel cell polyomavirus (MCPyV) is the first polyomavirus clearly associated with a human cancer, i.e. the Merkel cell carcinoma (MCC). Polyomaviruses are small naked DNA viruses that induce a robust polyclonal antibody response against the major capsid protein (VP1). However, the polyomavirus VP1 capsid protein epitopes have not been identified to date. The aim of this study was to identify the neutralizing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25812141
DOI: 10.1371/journal.pone.0121751
PMCID: PMC4374900

Genes

MCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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