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Article

Modeling the impact on virus transmission of <i>Wolbachia</i> -mediated blocking of dengue virus infection of <i>Aedes aegypti</i>

18 Mar 2015

Abstract excerpt

Dengue is the most common arboviral infection of humans and is a public health burden in more than 100 countries. Aedes aegypti mosquitoes stably infected with strains of the intracellular bacterium Wolbachia are resistant to dengue virus (DENV) infection and are being tested in field trials. To mimic field conditions, we experimentally assessed the vector competence of A. aegypti carrying the Wolbachia strains...

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PMID: 25787763
DOI: 10.1126/scitranslmed.3010370

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