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Article

Stem cells from human amniotic fluid exert immunoregulatory function via secreted indoleamine 2,3-dioxygenase1.

Journal of cellular and molecular medicine - 1 Jul 2015

Romani Rita, Pirisinu Irene, Calvitti Mario, Pallotta Maria Teresa, Gargaro Marco, Bistoni Giovanni, Vacca Carmine, Di Michele Alessandro, Orabona Ciriana, Rosati Jessica, Pirro Matteo, Giovagnoli Stefano, Matino Davide, Prontera Paolo, Rosi Gabriella, Grohmann Ursula, Talesa Vincenzo N, Donti Emilio, Puccetti Paolo, Fallarino Francesca

Abstract excerpt

Although human amniotic fluid does contain different populations of foetal-derived stem cells, scanty information is available on the stemness and the potential immunomodulatory activity of in vitro expanded, amniotic fluid stem cells. By means of a methodology unrequiring immune selection, we isolated and characterized different stem cell types from second-trimester human amniotic fluid samples (human amniotic...

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Identifiers

PMID: 25783564
DOI: 10.1111/jcmm.12534
PMCID: PMC4511357

Genes

IDO1
FOXP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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