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Article

Detailed hearing and vestibular profiles in the patients with COCH mutations.

The Annals of otology, rhinology, and laryngology - 1 May 2015

Tsukada Keita, Ichinose Aya, Miyagawa Maiko, Mori Kentaro, Hattori Mitsuru, Nishio Shin-Ya, Naito Yasushi, Kitajiri Shin-Ichiro, Usami Shin-Ichi

Abstract excerpt

OBJECTIVES: To evaluate the clinical features of Japanese DFNA9 families with mutations of the COCH gene. METHODS: Mutation screening was performed using targeted next-generation sequencing (NGS) for 63 previously reported deafness genes. The progression of hearing loss and vestibular dysfunction were evaluated by pure-tone audiometry, caloric testing, cVEMP, and computed dynamic posturography. RESULTS: We...

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Source

Identifiers

PMID: 25780252
DOI: 10.1177/0003489415573074

Genes

COCH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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