Article
Whole genome comparative analysis of transposable elements provides new insight into mechanisms of their inactivation in fungal genomes.
BMC genomics - 28 Feb 2015
Amselem Joëlle, Lebrun Marc-Henri, Quesneville Hadi
Abstract excerpt
BACKGROUND: Transposable Elements (TEs) are key components that shape the organization and evolution of genomes. Fungi have developed defense mechanisms against TE invasion such as RIP (Repeat-Induced Point mutation), MIP (Methylation Induced Premeiotically) and Quelling (RNA interference). RIP inactivates repeated sequences by promoting Cytosine to Thymine mutations, whereas MIP only methylates TEs at C...
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