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Article

Ancestral experience as a game changer in stress vulnerability and disease outcomes

11 Mar 2015

Abstract excerpt

Stress is one of the most powerful experiences to influence health and disease. Through epigenetic mechanisms, stress may generate a footprint that propagates to subsequent generations. Programming by prenatal stress or adverse experience in parents, grandparents, or earlier generations may thus be a critical determinant of lifetime health trajectories. Changes in regulation of microRNAs (miRNAs) by stress may...

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PMID: 25759985
DOI: 10.1002/bies.201400217

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