Transcriptional silencing and activation of paternal DNA during P lasmodium berghei zygotic development and transformation to oocyst

Abstract excerpt

The malaria parasite develops sexually in the mosquito midgut upon entry with the ingested blood meal before it can invade the midgut epithelium and embark on sporogony. Recent data have identified a number of distinct transcriptional programmes operating during this critical phase of the parasite life cycle. We aimed at characterizing the parental contribution to these transcriptional programmes and establish...

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