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Article

24-chromosome PCR for aneuploidy screening

20 Feb 2015

Abstract excerpt

PURPOSE OF REVIEW: The purpose of this study is to describe the many advantages of PCR-based comprehensive chromosome screening (CCS) methodologies and the importance of extensive preclinical validation. RECENT FINDINGS: The rigorous preclinical validation of quantitative real-time (q)PCR-based CCS involved an initial validation on cell lines, followed by a blinded evaluation on embryos. Comparison with...

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Share to Genetic Syndromes and Imprinting
Share to Genomic variations and chromosomal abnormalities
Share to Prenatal Screening and Diagnostics

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PMID: 25699477
DOI: 10.1097/gco.0000000000000167

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