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Article

Use of hTERT and HPV E6/E7 mRNA RT-qPCR TaqMan assays in combination for diagnosing high-grade cervical lesions and malignant tumors.

American journal of clinical pathology - 1 Mar 2015

Wang Hye-Young, Park Sunyoung, Kim Sunghyun, Lee Dongsup, Kim Geehyuk, Kim Yeun, Park Kwang Hwa, Lee Hyeyoung

Abstract excerpt

OBJECTIVES: Human papillomavirus (HPV) is a major cause of cervical cancer, which is the second most common cancer in women. HPV E6 initiates degradation of cellular tumor suppressor protein p53, induces human telomerase reverse transcriptase (hTERT) activity, and then leads to progressive cervical carcinogenesis. METHODS: In this study, the CervicGen HPV RT-qDX assay (Optipharm, Osong, Republic of Korea), which...

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PMID: 25696792
DOI: 10.1309/AJCPF2XGZ2XIQYQX

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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