Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Substrate-dependent activation of the Vibrio cholerae vexAB RND efflux system requires vexR.

PloS one - 1 Jan 2015

Taylor Dawn L, Ante Vanessa M, Bina X Renee, Howard Mondraya F, Bina James E

Abstract excerpt

Vibrio cholerae encodes six resistance-nodulation-division (RND) efflux systems which function in antimicrobial resistance, virulence factor production, and intestinal colonization. Among the six RND efflux systems, VexAB exhibited broad substrate specificity and played a predominant role in intrinsic antimicrobial resistance. The VexAB system was encoded in an apparent three gene operon that included vexR; which...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Drug Resistance, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Bacterial

Share to Genes, Bacterial

Share to Microbial Sensitivity Tests

Share to Operon

Share to Vibrio cholerae

Share to Virulence Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 25695834
DOI: 10.1371/journal.pone.0117890
PMCID: PMC4335029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Substrate-dependent activation of the Vibrio cholerae vexAB RND efflux system requires vexR.PMID 25695834Read ↗

Vibrio cholerae VexH encodes a multiple drug efflux pump that contributes to the production of cholera toxin and the toxin co-regulated pilus.Semantic proximity Read ↗

<i>Vibrio cholerae</i> OmpR represses the ToxR regulon in response to membrane intercalating agents that are prevalent in the human gastrointestinal tractSemantic proximity Read ↗

Overexpression of vmeTUV encoding a multidrug efflux transporter of Vibrio parahaemolyticus causes bile acid resistance.Semantic proximity Read ↗

Reciprocal regulation of resistance-nodulation-division efflux systems and the Cpx two-component system in Vibrio cholerae.Semantic proximity Read ↗

Expression of homologous RND efflux pump genes is dependent upon AcrB expression: implications for efflux and virulence inhibitor design.Semantic proximity Read ↗

Altered spectrum of multidrug resistance associated with a single point mutation in the Escherichia coli RND-type MDR efflux pump YhiV (MdtF).Semantic proximity Read ↗

The Salmonella enterica sv. Typhimurium smvA, yddG and ompD (porin) genes are required for the efficient efflux of methyl viologen.Semantic proximity Read ↗

The RND efflux pump EefABC is highly conserved within lineages of <i>E. coli</i> commonly associated with infectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.