Dissecting the determinants of malaria chronicity: why within-host models struggle to reproduce infection dynamics.

Abstract excerpt

The duration of infection is fundamental to the epidemiological behaviour of any infectious disease, but remains one of the most poorly understood aspects of malaria. In endemic areas, the malaria parasite Plasmodium falciparum can cause both acute, severe infections and asymptomatic, chronic infections through its interaction with the host immune system. Frequent superinfection and massive parasite genetic...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Antigens
• Share to Coinfection
• Share to Computer Simulation