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Article

Allogeneic donor availability for hematopoietic stem cell transplantation in children with sickle cell disease

7 Feb 2015

Abstract excerpt

Hematopoietic stem cell transplant is curative of sickle cell disease (SCD) but limited by donor availability. Searches for 85 patients with SCD without matched sibling donors from 2009-2013 using modern techniques (allele-level HLA matching for unrelated donors and higher total nucleated cell doses for umbilical cord blood (UCB)) showed potential match probabilities of 20% for 8/8 HLA-matched unrelated donors,...

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Identifiers

PMID: 25663074
DOI: 10.1002/pbc.25439

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