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Article

GJB2 as Well as SLC26A4 Gene Mutations are Prominent Causes for Congenital Deafness.

Cell biochemistry and biophysics - 1 Sept 2015

Fang Yuan, Gu Maosheng, Wang Chuanxia, Suo Feng, Wang Guangming, Xia Yujuan

Abstract excerpt

Mutations in gap junction proteins encoding beta connexions are believed to be a major cause for congenital hearing loss. The purpose of this study was to do comparative analyses of frequencies of most prominent mutations responsible for congenital deafness. Using fluorescence PCR method, the entire coding region of GJB2 gene, GJB3 gene, and SLC26A4 was analyzed. Direct DNA sequencing was used to analyze...

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Identifiers

PMID: 25649612
DOI: 10.1007/s12013-015-0562-3

Genes

GJB2
GJB3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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