Article
Predictable alteration of sequence recognition by RNA editing factors from Arabidopsis.
The Plant cell - 1 Feb 2015
Kindgren Peter, Yap Aaron, Bond Charles S, Small Ian
Abstract excerpt
RNA editing factors of the pentatricopeptide repeat (PPR) family show a very high degree of sequence specificity in the recognition of their target sites. A molecular basis for target recognition by editing factors has been proposed based on statistical correlations but has not been tested experimentally. To achieve this, we systematically mutated the pentatricopeptide motifs in the Arabidopsis thaliana RNA...
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