Article
Associations between TRPV4 genotypes and body mass index in Taiwanese subjects.
Molecular genetics and genomics : MGG - 1 Aug 2015
Duan De-Min, Wu Semon, Hsu Lung-An, Teng Ming-Sheng, Lin Jeng-Feng, Sun Yu-Chen, Cheng Ching-Feng, Ko Yu-Lin
Abstract excerpt
Body weight regulation is influenced neuronally via the hypothalamus, which strongly expresses TRPV4. TRPV4 deficiency in mice confers resistance against diet-induced obesity. We investigated the association between TRPV4 gene variants and body mass index (BMI) in Taiwanese subjects. A sample population of 617 Taiwanese subjects was enrolled, and ten TRPV4 gene polymorphisms were selected and genotyped. After...
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