Article
Highlighting nonlinear patterns in population genetics datasets.
Scientific reports - 30 Jan 2015
Alanis-Lobato Gregorio, Cannistraci Carlo Vittorio, Eriksson Anders, Manica Andrea, Ravasi Timothy
Abstract excerpt
Detecting structure in population genetics and case-control studies is important, as it exposes phenomena such as ecoclines, admixture and stratification. Principal Component Analysis (PCA) is a linear dimension-reduction technique commonly used for this purpose, but it struggles to reveal comple...
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