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Article

Defining phenotypes and disease progression in sarcomeric cardiomyopathies: contemporary role of clinical investigations.

Cardiovascular research - 1 Apr 2015

Olivotto Iacopo, d'Amati Giulia, Basso Cristina, Van Rossum Albert, Patten Monica, Emdin Michele, Pinto Yigal, Tomberli Benedetta, Camici Paolo G, Michels Michelle

Abstract excerpt

Mutations in cardiac sarcomere protein genes are associated with a variety of clinical phenotypes, including hypertrophic (HCM), dilated (DCM), and restrictive (RCM) cardiomyopathy as well as left ventricular non-compaction, with the overlap of morpho-functional manifestations in individual patients and families. Over time, initial phenotypes may undergo profound changes which determine clinical course and...

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PMID: 25631583
DOI: 10.1093/cvr/cvv024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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