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Article

In vitro and in vivo characterization of molecular determinants of virulence in reassortant betanodavirus

28 Jan 2015

Abstract excerpt

We previously reported that betanodavirus reassortant strains [redspotted grouper nervous necrosis virus/striped jack nervous necrosis virus (SJNNV)] isolated from Senegalese sole (Solea senegalensis) exhibited a modified SJNNV capsid amino acid sequence, with changes at aa 247 and 270. In the current study, we investigated the possible role of both residues as putative virulence determinants. Three recombinant...

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PMID: 25626678
DOI: 10.1099/vir.0.000064

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