Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evolutionary forward genomics reveals novel insights into the genes and pathways dysregulated in recurrent early pregnancy loss

12 Jan 2015

Abstract excerpt

STUDY QUESTION: Are the genes that gained novel expression in the endometria of Eutherian (placental) mammals more likely to be dysregulated in patients with endometrial-associated recurrent early pregnancy loss (REPL)? SUMMARY ANSWER: There was a significant enrichment of genes dysregulated in REPL patients among the Eutherian-specific endometrial genes. WHAT IS KNOWN ALREADY: Pregnancy loss is the most common...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gynecological conditions and treatments
Share to Reproductive System and Pregnancy
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25586782
DOI: 10.1093/humrep/deu355

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evolutionary forward genomics reveals novel insights into the genes and pathways dysregulated in recurrent early pregnancy lossPMID 25586782Read ↗

Evolutionary transcriptomics implicates new genes and pathways in human pregnancy and adverse pregnancy outcomesSemantic proximity Read ↗

Evolutionary transcriptomics implicates new genes and pathways in human pregnancy and adverse pregnancy outcomesSemantic proximity Read ↗

Dysregulation in Multiple Transcriptomic Endometrial Pathways Is Associated with Recurrent Implantation Failure and Recurrent Early Pregnancy LossSemantic proximity Read ↗

Endometrial gland-specific progestagen-associated endometrial protein and cilia gene splicing changes in recurrent pregnancy lossSemantic proximity Read ↗

Upregulation of immune genes in the proliferative phase endometrium enables classification into women with recurrent pregnancy loss versus controlsSemantic proximity Read ↗

Asynchronous and pathological windows of implantation: two causes of recurrent implantation failure†Semantic proximity Read ↗

Specific and extensive endometrial deregulation is present before conception in IVF/ICSI repeated implantation failures (IF) or recurrent miscarriagesSemantic proximity Read ↗

An endometrial gene expression signature accurately predicts recurrent implantation failure after IVFSemantic proximity Read ↗

Identifying genes underlying parallel evolution of stromal resistance to placental and cancer invasionSemantic proximity Read ↗

Transcriptional changes through menstrual cycle reveal a global transcriptional derepression underlying the molecular mechanism involved in the window of implantationSemantic proximity Read ↗

Application of functional genomics to primate endometrium: insights into biological processesSemantic proximity Read ↗

Integrative Analyses of Uterine Transcriptome and MicroRNAome Reveal Compromised LIF-STAT3 Signaling and Progesterone Response in the Endometrium of Patients with Recurrent/Repeated Implantation Failure (RIF)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.