Article
Frequency distribution of apolipoprotein E genotypes in elderly population and relationship with senile dementia.
Journal of neurosurgical sciences - 1 Feb 2020
Huang Wen, Chen Man'e, Zhang Yingqi, Zhao Ping, Yao Guo'en, Zhou Huadong
Abstract excerpt
BACKGROUND: The aim of this study was to determine the relationship between apolipoprotein E (ApoE)-ε4 genotype and senile dementia (SD) by analyzing the ApoE allelic frequency distributions among the elderly Han Chinese population. METHODS: For this purpose, a total of 316 Chongqing residents aged ≥60 years were classified as SD or control groups following the criteria of National Institute of Neurological and...
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