Article
[Genotyping and evaluation of infection dynamics in a Colombian isolate of Leptospira santarosai in hamster as an experimental model].
Biomedica : revista del Instituto Nacional de Salud - 1 Jan 2000
Agudelo-Flórez Piedad, Durango Harold, Aranzazu Diego, Rodas Juan David, Travi Bruno
Abstract excerpt
INTRODUCTION: Is necessary to develop models for the study of leptospirosis. OBJECTIVE: To genotype a Colombian strain of Leptospira isolated from a human with Weil´s syndrome and to evaluate its infection dynamics in the hamster experimental model. MATERIALS AND METHODS: Genotyping was performed by amplification and sequence analysis of the rrs 16S and lipL32 genes. The median lethal dose was determined in...
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