Article
Microsatellite markers reveal low levels of population sub-structuring of Plasmodium falciparum in southwestern Nigeria.
Malaria journal - 13 Dec 2014
Oyebola Muyiwa K, Idowu Emmanuel T, Nyang Haddy, Olukosi Yetunde A, Otubanjo Olubunmi A, Nwakanma Davis C, Awolola Samson T, Amambua-Ngwa Alfred
Abstract excerpt
BACKGROUND: Genetic diversity studies provide evidence of Plasmodium falciparum differentiation that could affect fitness and adaptation to drugs and target antigens for vaccine development. This study describes the genetic structure of P. falciparum populations in urban and rural sites from southwestern Nigeria. METHODOLOGY: Ten neutral microsatellite loci were genotyped in 196 P. falciparum infections from...
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