Tocotrienols promote apoptosis in human breast cancer cells by inducing poly(<scp>ADP</scp>‐ribose) polymerase cleavage and inhibiting nuclear factor kappa‐B activity

Abstract excerpt

OBJECTIVES: Tocotrienols and tocopherols are members of the vitamin E family, with similar structures; however, only tocotrienols have been reported to achieve potent anti-cancer effects. The study described here has evaluated anti-cancer activity of vitamin E to elucidate mechanisms of cell death, using human breast cancer cells. MATERIALS AND METHODS: Anti-cancer activity of a tocotrienol-rich fraction (TRF)...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Antioxidant Activity and Oxidative Stress