Article
Significance of association of HLA-C and HLA-E with psoriatic arthritis.
Human immunology - 1 Dec 2014
Sokolik Renata, Gębura Katarzyna, Iwaszko Milena, Świerkot Jerzy, Korman Lucyna, Wiland Piotr, Bogunia-Kubik Katarzyna
Abstract excerpt
Psoriatic arthritis (PsA) is a complex genetic disorder that results from an interplay between multiple genetic and environmental factors. The aim of the study was to assess the significance of the association between the HLA-C and HLA-E allelic groups and PsA. Our results confirm the association between HLA-C(∗)06 and PsA (OR=5.16, p<0.0001). Furthermore, HLA-C(∗)06-positive patients develop more severe disease...
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