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Article

Meta-analysis of Hsa-mir-499 polymorphism (rs3746444) for cancer risk: evidence from 31 case-control studies.

BMC medical genetics - 30 Nov 2014

Chen Chen, Yang Shenglan, Chaugai Sandip, Wang Yan, Wang Dao Wen

Abstract excerpt

BACKGROUND: MicroRNAs (miRNAs) are a family of endogenous, small and non-coding RNAs that regulate gene expression negatively at the post-transcriptional level by suppressing translation or degrading target mRNAs, and are involved in diverse biological and pathological processes. Single nucleotide polymorphisms (SNPs) which are located in the miRNA-coding genes may participate in the process of development and...

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PMID: 25433484
DOI: 10.1186/s12881-014-0126-1
PMCID: PMC4411927

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