Genomic dissection of travel-associated extended-spectrum-beta-lactamase-producing Salmonella enterica serovar typhi isolates originating from the Philippines: a one-off occurrence or a threat to effective treatment of typhoid fever?

doi:10.1128/JCM.03104-14

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Genomic dissection of travel-associated extended-spectrum-beta-lactamase-producing Salmonella enterica serovar typhi isolates originating from the Philippines: a one-off occurrence or a threat to effective treatment of typhoid fever?

Journal of clinical microbiology - 1 Feb 2015

Hendriksen Rene S, Leekitcharoenphon Pimlapas, Mikoleit Matthew, Jensen Jacob Dyring, Kaas Rolf Sommer, Roer Louise, Joshi Heena B, Pornruangmong Srirat, Pulsrikarn Chaiwat, Gonzalez-Aviles Gladys D, Reuland E Ascelijn, Al Naiemi Nashwan, Wester Astrid Louise, Aarestrup Frank M, Hasman Henrik

Abstract excerpt

One unreported case of extended-spectrum-beta-lactamase (ESBL)-producing Salmonella enterica serovar Typhi was identified, whole-genome sequence typed, among other analyses, and compared to other available genomes of S. Typhi. The reported strain was similar to a previously published strain harboring blaSHV-12 from the Philippines and likely part of an undetected outbreak, the first of ESBL-producing S. Typhi.

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PMID: 25428145
DOI: 10.1128/JCM.03104-14
PMCID: PMC4298498

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