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Article

Characterization of Treponema denticola mutants defective in the major antigenic proteins, Msp and TmpC.

PloS one - 1 Jan 2014

Abiko Yuki, Nagano Keiji, Yoshida Yasuo, Yoshimura Fuminobu

Abstract excerpt

Treponema denticola, a gram-negative and anaerobic spirochete, is associated with advancing severity of chronic periodontitis. In this study, we confirmed that two major antigenic proteins were Msp and TmpC, and examined their physiological and pathological roles using gene-deletion mutants. Msp formed a large complex that localized to the outer membrane, while TmpC existed as a monomer and largely localized to...

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Identifiers

PMID: 25401769
DOI: 10.1371/journal.pone.0113565
PMCID: PMC4234677

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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