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Phage antibody display libraries: a powerful antibody discovery platform for immunotherapy

14 Nov 2014

Abstract excerpt

Phage display technology (PDT), a combinatorial screening approach, provides a molecular diversity tool for creating libraries of peptides/proteins and discovery of new recombinant therapeutics. Expression of proteins such as monoclonal antibodies (mAbs) on the surface of filamentous phage can permit the selection of high affinity and specificity therapeutic mAbs against virtually any target antigen. Using a...

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PMID: 25394539
DOI: 10.3109/07388551.2014.958978

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