Article
Obesity-associated gene FTO rs9939609 polymorphism in relation to the risk of tuberculosis.
BMC infectious diseases - 7 Nov 2014
Feng Yan, Wang Fengliang, Pan Hongqiu, Qiu Sangsang, Lü Jieqiong, Wu Liang, Wang Jianming, Lu Cheng
Abstract excerpt
BACKGROUND: Obesity is known to affect cell-mediated immune responses. Recent studies have revealed that genetic polymorphisms in the fat mass and obesity associated (FTO) gene are related to human obesity. We hypothesize that this gene may also play a role in the risk of immune-related infectious diseases such as tuberculosis. METHODS: This case-control study included 1625 pulmonary tuberculosis cases and 1570...
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