Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Congenital and acquired ADAMTS13 deficiency: Two mechanisms, one patient.

Journal of clinical apheresis - 1 Aug 2015

Ferrari Barbara, Cairo Andrea, Pontiggia Silvia, Mancini Ilaria, Masini Luciano, Peyvandi Flora

Abstract excerpt

Thrombotic thrombocytopenic purpura (TTP) is a life-threatening microangiopathy with a heterogeneous and largely unpredictable course. It is caused by ADAMTS13 deficiency, that can be either congenital or due to anti-ADAMTS13 autoantibodies development. ADAMTS13 deficiency is necessary but not always sufficient to cause acute clinical manifestations and trigger factors may be needed. We report the case of a woman...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ADAM Proteins
Share to ADAMTS13 Protein
Share to Autoantibodies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Environmental Exposure

Share to Family Health

Share to Point Mutation

Share to Purpura, Thrombotic Thrombocytopenic

Share to Ticlopidine

Source

Identifiers

PMID: 25367325
DOI: 10.1002/jca.21366

Genes

ADAMTS13

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Congenital and acquired ADAMTS13 deficiency: Two mechanisms, one patient.PMID 25367325Read ↗

Acquired thrombotic thrombocytopenic purpura without detectable anti-ADAMTS13 antibodies: a possible underlying autoimmune mechanism.Semantic proximity Read ↗

The International Hereditary Thrombotic Thrombocytopenic Purpura Registry: key findings at enrollment until 2017Semantic proximity Read ↗

Inherited ADAMTS13 mutations associated with Thrombotic Thrombocytopenic Purpura: a short review and update.Semantic proximity Read ↗

A case of congenital thrombotic thrombocytopenic purpura presenting with renal dysfunction in adulthood caused by a novel compound heterozygous ADAMTS13 mutation.Semantic proximity Read ↗

A first case of congenital TTP on the African continent due to a new homozygous mutation in the catalytic domain of ADAMTS13.Semantic proximity Read ↗

Child-onset and adolescent-onset acquired thrombotic thrombocytopenic purpura with severe ADAMTS13 deficiency: a cohort study of the French national registry for thrombotic microangiopathy.Semantic proximity Read ↗

[From gene to disease; congenital thrombotic thrombocytopenic purpura due to mutations in the ADAMTS13 gene].Semantic proximity Read ↗

Congenital thrombotic thrombocytopenic purpura (cTTP) with two novel mutations.Semantic proximity Read ↗

Congenital thrombotic thrombocytopenic purpura with novel mutations in three unrelated Turkish children.Semantic proximity Read ↗

Hereditary Thrombotic Thrombocytopenic Purpura.Semantic proximity Read ↗

First reported case of congenital thrombotic thrombocytopenic purpura in Taiwan with novel mutation of ADAMTS13 gene.Semantic proximity Read ↗

Congenital thrombotic thrombocytopenic purpura related to a novel mutation in ADAMTS13 gene and management during pregnancy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.