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Article

Promotive role of recombinant HE4 protein in proliferation and carboplatin resistance in ovarian cancer cells

17 Oct 2014

Abstract excerpt

Available evidence on the proliferation-promoting effect of HE4 remains controversial, and few studies have been carried out on the molecular mechanism of chemoresistance mediated by HE4. The aim of the present study was to investigate the influence of exogenous recombinant HE4 protein on proliferation and resistance to carboplatin in ovarian cancer cells. The human ovarian cancer cell line (SKOV-3) was exposed...

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Identifiers

PMID: 25354091
DOI: 10.3892/or.2014.3549

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