Article
Common variants associated with general and MMR vaccine-related febrile seizures.
Nature genetics - 1 Dec 2014
Feenstra Bjarke, Pasternak Björn, Geller Frank, Carstensen Lisbeth, Wang Tongfei, Huang Fen, Eitson Jennifer L, Hollegaard Mads V, Svanström Henrik, Vestergaard Mogens, Hougaard David M, Schoggins John W, Jan Lily Yeh, Melbye Mads, Hviid Anders
Abstract excerpt
Febrile seizures represent a serious adverse event following measles, mumps and rubella (MMR) vaccination. We conducted a series of genome-wide association scans comparing children with MMR-related febrile seizures, children with febrile seizures unrelated to vaccination and controls with no history of febrile seizures. Two loci were distinctly associated with MMR-related febrile seizures, harboring the...
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