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Expression, function, and regulation of the testis-enriched heat shock HSPA2 gene in rodents and humans

24 Oct 2014

Abstract excerpt

The HSPA2 gene is a poorly characterized member of the HSPA (HSP70) family. HSPA2 was originally described as testis-specific and expressed at the highest level in pachytene spermatocytes of rodents, the expression of which is not induced by heat shock. HSPA2 is crucial for male fertility. However, recent advances have shown that HSPA2 is expressed in various tumors and in certain types of somatic tissues. In...

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PMID: 25344376
DOI: 10.1007/s12192-014-0548-x

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