Article
Structural insights into the negative regulation of BRI1 signaling by BRI1-interacting protein BKI1.
Cell research - 1 Nov 2014
Wang Jie, Jiang Jianjun, Wang Jue, Chen Lei, Fan Shi-Long, Wu Jia-Wei, Wang Xuelu, Wang Zhi-Xin
Abstract excerpt
Brassinosteroids (BRs) are essential steroid hormones that have crucial roles in plant growth and development. BRs are perceived by the cell-surface receptor-like kinase brassinosteroid insensitive 1 (BRI1). In the absence of BRs, the cytosolic kinase domain (KD) of BRI1 is inhibited by its auto-inhibitory carboxyl terminus, as well as by interacting with an inhibitor protein, BRI1 kinase inhibitor 1 (BKI1). How...
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