Article
Novel cyclic di-GMP effectors of the YajQ protein family control bacterial virulence.
PLoS pathogens - 1 Oct 2014
An Shi-qi, Caly Delphine L, McCarthy Yvonne, Murdoch Sarah L, Ward Joseph, Febrer Melanie, Dow J Maxwell, Ryan Robert P
Abstract excerpt
Bis-(3',5') cyclic di-guanylate (cyclic di-GMP) is a key bacterial second messenger that is implicated in the regulation of many critical processes that include motility, biofilm formation and virulence. Cyclic di-GMP influences diverse functions through interaction with a range of effectors. Our knowledge of these effectors and their different regulatory actions is far from complete, however. Here we have used...
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