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Uracil-DNA glycosylase (UNG) rs246079 G/A polymorphism is associated with decreased risk of esophageal cancer in a Chinese population.

Medical oncology (Northwood, London, England) - 1 Nov 2014

Yin Jun, Sang Yonghua, Zheng Liang, Wang Liming, Yuan Luorongxin, Liu Chao, Wang Xu, Shi Yijun, Shao Aizhong, Ding Guowen, Chen Suocheng, Tang Weifeng, Gu Haiyong

Abstract excerpt

Esophageal cancer is the sixth leading cause of cancer-associated death worldwide. In addition to environmental risk factors, genetic factors might play an important role in esophageal cancer carcinogenesis. We conducted a hospital-based case-control study to evaluate the association between functional single nucleotide polymorphisms (SNPs) in uracil-DNA glycosylase (UNG) and the development of esophageal cancer....

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PMID: 25301111
DOI: 10.1007/s12032-014-0272-5

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UNG

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