Article
A novel Pseudomonas aeruginosa strain with an oprD mutation in relation to a nosocomial respiratory infection outbreak in an intensive care unit.
Journal of clinical microbiology - 1 Dec 2014
Yan Yingjun, Yao Xiangyu, Li Haijing, Zhou Zhonghua, Huang Wenfang, Stratton Charles W, Lu Chung-Dar, Tang Yi-Wei
Abstract excerpt
Seven imipenem-resistant Pseudomonas aeruginosa isolates were recovered from the sputum samples of pneumonia patients in southwestern China. They had identical antibiotic resistance patterns and indistinguishable pulsed-field gel electrophoresis profiles. Nucleotide sequence analysis revealed a 4-bp (AGTC) insertion in the oprD gene, resulting in a frameshift in the cognate open reading frame. These isolates...
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